Hi Matt,
let's calculate: I run 22/9=2,44... and the wheel perimeter is roughly 1,6 m. So I ride about 3,9 m per crank rotation. With 39/16=2,4375 and 16*2,54*pi=1,28 m you would have 3,12 m per crank rotation. So I would say not too bad. But maybe a little less would be good. Less than 32T could be a little too much.