Some things might feel weird at first.
When I swapped from my ABT thing to my Delta 4, the geometry of the two frames were completely different. The bottom bracket was much lower on the Delta 4 so I had to almost step up to the pegs, rather than step down. "Sounds kinda funny, but it's true"
Really it's all depending on what is different between the frame you had and the one your getting. If the are close in geo, you shouldn't have much of a problem at all.
You'll get the hang of it no matter what